Molecular Biology Grade Antibiotic with Great Performance in a wide range of Applications
Tetracycline Hydrochloride is an antibiotic active against a wide range of gram-negative and gram-positive bacteria. The parent compound chlortetracycline was first isolated from Streptomyces aureofaciens in 1947. Soon after, other natural tetracyclines were isolated, including tetracycline, for which the family of molecules is named. The tetracyclines exert their antibiotic effect primarily by binding to the bacterial ribosome and halting protein synthesis. Upon binding the ribosome, the tetracyclines allosterically inhibit binding of the amino acyl-tRNA at the acceptor site, and protein synthesis ceases.