Senescence Detection Kit (SA-ß-gal Staining)
For a Fast, Convenient & Easy activity measure of SA-B-Gal in Cells Cultures
Senescence Detection Kit is a Fast, Convenient & Easy-to-use kit that measures activity of SA-B-Gal in cells cultures by hydrolysis of X-gal, which results in the accumulation of a distinctive blue color in senescent cells.
Senescence cells display a phenotype like increase of cell size, distinctive flat morphology, changes in gene expression and activity of senescence-associate ß-galactosidase (SA-ß-gal).
It represents tumor suppressor mechanism for this reason cellular senescence has become an increasingly target in the development of novel therapeutics.