HigherPurity™ PCR Clean-Up Magnetic Beads
Magnetic beads for efficient PCR clean-up and DNA purification ≥100 bp, optimized for manual and automated workflows
HigherPurity™ PCR Clean-Up Magnetic Beads are an advanced solution for fast and reliable DNA purification. These PCR clean-up magnetic beads use Solid-Phase Reversible Immobilization (SPRI) technology to efficiently bind DNA fragments ≥100 bp while removing salts, primers, dNTPs, enzymes, and other impurities.
Designed for both manual and automated workflows, HigherPurity™ PCR Clean-Up Magnetic Beads ensure reproducible, high-yield recovery of PCR amplicons. Their optimized formulation provides superior scalability for sequencing, cloning, genotyping, and NGS library preparation, making them a trusted choice for PCR product clean-up.
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Price: 91.20 € – 3,197.90 €
Detailed information:
Advantages & Features
- Selective binding: Purifies DNA ≥100 bp.
- High recovery: Removes salts, enzymes, primers, dNTPs, and other impurities.
- Scalable: Compatible with both manual and automated platforms.
- Time-saving: Avoids centrifugation and filtration steps.
- Flexible format: Works in 96- and 384-well plates.
- Fast protocol: Superior turnaround compared to traditional clean-up methods.
Specifications
Includes
Includes for 60 mL:
– 60 mL HigherPurity™ PCR Clean-Up Magnetic Beads Kit (sufficient for the Purifications of 1,666 samples of 20 µL or 6,667 samples of 5 µL).
– Protocol instructions.
Download documentation
Datasheet MSDSApplication NoteApplications
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PCR clean-up for downstream applications.
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Sequencing and fragment analysis.
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Genotyping and cloning workflows.
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Next-Generation Sequencing (NGS) library preparation.
Tables & Figures
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Quality Control
Each lot is tested for:
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DNA recovery efficiency using PCR fragments.
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Reproducibility in multiple clean-up assays.
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Absence of nucleases and contaminants.
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Advice
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Do not freeze beads, as freezing may reduce binding efficiency.
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Mix thoroughly before use to ensure homogeneity.
Storage, Shipping & Guarantee
- Shipment at Gel Pack.
- Storage: Store protected from light at 4°C upon arrival, for up to 12 months. Beads appear brown and may settle during storage. Shake the reagent well to a homogenous appearance before use.
Citations
- Peralta-Sánchez, J. M., Rabelo-Ruiz, M., Martín-Platero, A. M., Arizcun, M., Galafat, A., Alarcón-López, F. J., … & Martínez-Bueno, M. (2025). Effects of dietary inclusion of crude or hydrolyzed Arthrospira platensis on intestinal microbiota in gilthead seabream (Sparus aurata) fry. Discover Animals, 2(1), 99.
- Slavková, M. (2025). Virus-host cell interactions: Examples of gammaretroviral transcription control and somatic hypermutation targeting of SV40 enhancer.
- Peralta-Sánchez, J. M., Rabelo-Ruiz, M., Martín-Platero, A. M., Vizcaíno, A. J., Flores-Moreno, S., Macías-Vidal, J., … & Martínez-Bueno, M. (2024). Microalgae and phytase dietary supplementation improved growth and gut microbiota in juvenile European seabass (Dicentrarchus labrax). BMC genomics, 25.
- Rabelo-Ruiz, M., Peralta-Sánchez, J. M., Martín-Platero, A. M., Ruiz, A. J., Agraso, M. D. M., Bermúdez, L., … & Martínez-Bueno, M. (2023). Allium-Derived Compound Propyl Propane Thiosulfonate (PTSO) Reduces Vibrio Populations and Increases Body Weight of European Seabass (Dicentrarchus labrax) Juveniles. Antibiotics, 12(1), 134.
- Rabelo Ruiz, M. (2022). Respuesta del microbioma intestinal de animales del sector avícola, porcino y piscícola al tratamiento con probióticos y extractos de aliáceas.
- Garg, Nupur, et al. “Development of a Loop-mediated isothermal amplification (LAMP) technique for specific and early detection of Mycobacterium leprae in clinical samples.” Scientific Reports 11.1 (2021): 1-12.
- Pitusi, Vanessa, et al. “The occurrence of Nematoda in coastal sea ice on Svalbard (European Arctic) determined with the 18S small subunit rRNA gene.” Polar Biology (2021): 1-10.
- Davidov, K., Iankelevich-Kounio, E., Yakovenko, I., Koucherov, Y., Rubin-Blum, M., & Oren, M. (2020). Identification of plastic-associated species in the Mediterranean Sea using DNA metabarcoding with Nanopore MinION. Scientific Reports, 10(1), 1-11.
Safety Statements
This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals. For more info, please check its Material Safety Data Sheet available in this website.
Customers Review
Synonym(s)
PCR cleanup magnetic beads, DNA purification magnetic beads, PCR purification beads, Nucleic acid cleanup beads, Magnetic bead DNA purification
Also known as:
- Spanish: Perlas magnéticas para limpieza de PCR, Purificación de ADN con perlas magnéticas, Limpieza de PCR
- French: Billes magnétiques pour purification PCR, Purification ADN par billes magnétiques, Nettoyage PCR
- German: Magnetische Beads zur PCR-Reinigung, DNA-Reinigung mit Magnetbeads, PCR-Aufreinigung
- Italian: Perle magnetiche per pulizia PCR, Purificazione DNA con perle magnetiche, Pulizia PCR
FAQs
Q: What DNA fragment sizes can be purified?
A: DNA ≥100 bp is efficiently recovered.
Q: Are the beads automation-compatible?
A: Yes, they are fully compatible with robotic liquid handling platforms.
Q: Can I use them for NGS library prep?
A: Yes, they are widely used for NGS workflows requiring PCR product clean-up.
5 reviews for HigherPurity™ PCR Clean-Up Magnetic Beads
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Javier Molina –
These magnetic beads have become part of our routine PCR cleanup workflow before sequencing and cloning experiments. Handling with a magnetic rack is straightforward and the process scales well when processing many samples simultaneously. They have helped simplify sample preparation in our group.
Oliver Grant –
We incorporated these beads for post-PCR cleanup before sequencing workflows. The protocol is easy to implement and works smoothly with magnetic rack handling already established in our lab. It has reduced hands-on complexity during larger batch processing days.
Sophie Lambert –
We incorporated these magnetic beads into our PCR clean-up workflow for routine fragment purification before downstream applications. The protocol described on the product page is straightforward to follow and integrates well with standard magnetic rack setups. It has been practical for handling multiple samples in parallel without adding complexity to the workflow.
Mateo Silva –
We added these beads for post-PCR clean-up before downstream applications. Magnetic handling is practical when processing multiple samples and fits well with our bench routine. Good option for keeping workflows efficient.
Hannah Lewis –
We adopted these beads for post-PCR clean-up in a sequencing support lab. Handling was simple with magnetic racks already in place, and the workflow fits well into higher sample numbers. A convenient alternative for routine purification steps.